Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24115254 | 0.80 | GRM5 (0.55) | GRM5GRM2KDM4EMEN1ALDH1A1 | |
| SCHEMBL24115280 | 0.71 | GRM5 (0.53) | GRM5GRM2KDM4EMEN1ALDH1A1 | |
| SCHEMBL26864406 | 0.65 | ALDH1A1 (0.48) | ALDH1A1TDP1HTT | |
| SCHEMBL26864412 | 0.64 | ANPEP (0.45) | ALDH1A1TDP1 | |
| SCHEMBL13973820 | 0.63 | ANPEP (0.44) | ALDH1A1TDP1 | |
| SCHEMBL26864409 | 0.61 | KISS1R (0.47) | ALDH1A1TDP1 | |
| SCHEMBL20342062 | 0.61 | ANPEP (0.62) | GRM5GRM2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL20342227 | 0.61 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL24115234 | 0.61 | PKM (0.50) | ALDH1A1 | |
| SCHEMBL20342061 | 0.60 | ANPEP (0.41) | ALDH1A1BLMKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3925667-A1 | SELECTIVE TMPRSS2 INHIBITORS AND MEDICAL USE THEREOF | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-12-22 | — | — | EP | disclosed |