Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 7/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532663 | 0.90 | USP30 (0.61) | USP30HDAC4HDAC6PARP1GABRA5 | |
| SCHEMBL31532672 | 0.89 | USP30 (0.56) | USP30HDAC4HDAC6PARP1GABRA5 | |
| SCHEMBL31532676 | 0.89 | USP30 (0.55) | USP30PARP1GABRA5BTK | |
| SCHEMBL31532675 | 0.87 | USP30 (0.59) | USP30HDAC4HDAC6PARP1GABRA5 | |
| SCHEMBL1770908 | 0.87 | USP30 (0.59) | USP30HDAC4HDAC6PARP1GABRA5 | |
| SCHEMBL31532636 | 0.87 | USP30 (0.59) | USP30HDAC4HDAC6PARP1GABRA5 | |
| SCHEMBL31532575 | 0.87 | USP30 (0.59) | USP30HDAC4HDAC6PARP1GABRA5 | |
| SCHEMBL31532587 | 0.87 | USP30 (0.59) | USP30HDAC4HDAC6PARP1GABRA5 | |
| SCHEMBL31532654 | 0.87 | USP30 (0.59) | USP30HDAC4HDAC6PARP1GABRA5 | |
| SCHEMBL1564849 | 0.85 | CNR1 (0.57) | USP30HDAC4HDAC6PARP1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4552639-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-14 | — | — | EP | disclosed |