Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110289 | 1.00 | NPSR1 (0.53) | NPSR1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL10085163 | 1.00 | NPSR1 (0.53) | NPSR1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL21340181 | 1.00 | NPSR1 (0.53) | NPSR1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL18613033 | 1.00 | NPSR1 (0.53) | NPSR1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL10078381 | 1.00 | NPSR1 (0.53) | NPSR1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL2904621 | 0.90 | L3MBTL1 (0.44) | NPSR1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL20246743 | 0.84 | SMN1; SMN2 (0.48) | NPSR1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL13638135 | 0.82 | SMN1; SMN2 (0.56) | NPSR1HPGDKMT2AEPHX1SMN1; SMN2 | |
| SCHEMBL11570524 | 0.76 | NPSR1 (0.60) | NPSR1NPC1RAB9AHPGDKMT2A | |
| SCHEMBL11569599 | 0.76 | NPSR1 (0.60) | NPSR1NPC1RAB9AHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025099238-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-15 | — | — | WO | disclosed |
| EP-4552639-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF GASTROINTESTINAL STROMAL TUMOR (GIST) | Universität Duisburg-Essen (DE) | 2025-05-14 | — | — | EP | disclosed |