Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 8/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14110289 | 0.84 | NPSR1 (0.53) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL18613033 | 0.84 | NPSR1 (0.53) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL31532555 | 0.84 | NPSR1 (0.53) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL10085163 | 0.84 | NPSR1 (0.53) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL10078381 | 0.84 | NPSR1 (0.53) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL21340181 | 0.84 | NPSR1 (0.53) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL2904621 | 0.77 | L3MBTL1 (0.44) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL25894262 | 0.73 | POLB (0.44) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A | |
| SCHEMBL25894179 | 0.73 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9AKMT2AHPGD | |
| SCHEMBL2412758 | 0.72 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9ANPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892525-B1 | METHODS OF TREATING MUSCULAR DYSTROPHY | UNIV NEVADA RENO (US) | 2018-06-13 | — | — | EP | disclosed |