SCHEMBL384725

SCHEMBL384725

Oc1cccc(OCc2ccccc2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.71
CYP4F2 P78329 1/20 0.66
CYP4A11 Q02928 1/20 0.66
MAOB P27338 5/20 0.65
NR4A2 P43354 1/20 0.64
CYP1A2 P05177 2/20 0.62
LMNA P02545 1/20 0.62
PTGS1 P23219 1/20 0.62
SLC6A2 P23975 1/20 0.62
CYP2C19 P33261 1/20 0.62
PTGS2 P35354 1/20 0.62
SLC6A3 Q01959 1/20 0.62
HIF1A Q16665 1/20 0.62
HDAC6 Q9UBN7 1/20 0.62
DRD2 P14416 1/20 0.61
DRD4 P21917 1/20 0.61
ADRA1D P25100 1/20 0.61
ADRA1A P35348 1/20 0.61
ADRA1B P35368 1/20 0.61
DRD3 P35462 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29548398 1.00 APP (0.71) APPCYP4F2CYP4A11MAOBNR4A2
Phenol SCHEMBL28049001 0.98 APP (0.69) APPCYP4F2CYP4A11MAOBNR4A2
Formaldehyde SCHEMBL28868941 0.94 APP (0.65) APPCYP4F2CYP4A11MAOBNR4A2
SCHEMBL6428535 0.93 APP (0.63) APPCYP4F2CYP4A11MAOBNR4A2
SCHEMBL6910779 0.90 FFAR1 (0.60) APPCYP4F2CYP4A11MAOBNR4A2
SCHEMBL27735405 0.88 APP (0.77) APPCYP4F2CYP4A11MAOBCYP1A2
SCHEMBL13192629 0.88 LMNA (0.62) APPCYP4F2CYP4A11MAOBNR4A2
SCHEMBL1268719 0.87 MAOB (0.81) CYP4F2CYP4A11MAOBNR4A2CYP1A2
SCHEMBL11019942 0.85 DRD2 (0.55) APPCYP4F2CYP4A11MAOBNR4A2
Benzylphenylether SCHEMBL6439510 0.85 LMNA (0.83) APPCYP4F2CYP4A11MAOBNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1096 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398100-B2 Methods and intermediates for preparing hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide MYLAN LABORATORIES LIMITED (IN) 2025-08-26 US claimed
CN-114957152-B Synthesis method of benzoxazole compound 湖南第一师范学院 2023-11-17 CN claimed
US-20220380307-A1 METHODS AND INTERMEDIATES FOR PREPARING HYDROCHLORIDE SALT OF 5-[3-(3-HYDROXYPHENOXY)AZETIDIN-1-YL]-5-METHYL-2,2-DIPHENYLHEXANAMIDE MYLAN LABORATORIES LIMITED (IN) 2022-12-01 US claimed
CN-114957152-A Synthetic method of benzoxazole compound 湖南第一师范学院 2022-08-30 CN claimed
EP-3990091-A1 METHODS AND INTERMEDIATES FOR PREPARING HYDROCHLORIDE SALT OF 5-[3-(3-HYDROXYPHENOXY)AZETIDIN-1-YL]-5-METHYL-2,2-DIPHENYLHEXANAMIDE Mylan Laboratories Ltd. (IN) 2022-05-04 EP claimed
WO-2020261160-A1 METHODS AND INTERMEDIATES FOR PREPARING HYDROCHLORIDE SALT OF 5-[3-(3-HYDROXYPHENOXY)AZETIDIN-1-YL]-5-METHYL-2,2-DIPHENYLHEXANAMIDE MYLAN LABORATORIES LIMITED (IN) 2020-12-30 WO claimed
US-20140135297-A1 AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION ISP INVESTMENTS INC. (US) 2014-05-15 US claimed
WO-2012170841-A1 AN AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION ISP INVESTMENTS INC. (US) 2012-12-13 WO claimed
CN-101235039-B Chemical total synthesis method for wedelolactone UNIV SHANGHAI JIAOTONG 2010-11-03 CN claimed
CN-101768086-A Amino methanol derivant and salt compound thereof as well as synthesizing method and medical application thereof BEIJING FUKA BIOTECHNOLOGY CO 2010-07-07 CN claimed
EP-1537201-A1 HARD SURFACE TREATING COMPOSITIONS Reckitt Benckiser Inc. (US) 2005-06-08 EP claimed
WO-2004024861-A1 HARD SURFACE TREATING COMPOSITIONS RECKITT BENCKISER INC (US) 2004-03-25 WO claimed
CN-1443153-A Process for preparation of enantiomerically pure pyrethroid insecticides SYNGENTA LTD (GB) 2003-09-17 CN claimed
EP-0498724-B1 Esters of 3-(3,3,3-trifluoro-2-chloropropenyl)-2,2-dimethyl-cyclopropanecarboxylic acid, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1996-05-15 EP claimed
EP-0476708-B1 (Trifluoromethyl)vinyl pyrethroid derivatives, their use as pesticides, process for their preparation, and intermediates of that process ROUSSEL UCLAF (FR) 1995-11-08 EP claimed
WO-1995020637-A2 HYDROCARBON OIL-AQUEOUS FUEL AND ADDITIVE COMPOSITIONS MEG S.N.C. DI SCOPELLITI SOFIA & C. (IT) 1995-08-03 WO claimed
US-5082832-A Pesticides ROUSSEL UCLAF (FR) 1992-01-21 US claimed
EP-0228942-B1 IODINE-SUBSTITUTED CYCLOPROPANECARBOXYLIC-ACID DERIVATIVES, THEIR PREPARATION, THEIR USE AS PLANT AND ANIMAL PARASITICIDES AND COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1990-05-23 EP claimed
EP-0018894-B1 ESTERS OF ALLETHROLONE DERIVATIVES AND CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM ROUSSEL-UCLAF (FR) 1982-02-17 EP claimed
US-4275241-A BY DICHROMATE OXIDATION IN AQUEOUS SULFURIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1981-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220380307-A1 METHODS AND INTERMEDIATES FOR PREPARING HYDROCHLORIDE SALT OF 5-[3-(3-HYDROXYPHENOXY)AZETIDIN-1-YL]-5-METHYL-2,2-DIPHENYLHEXANAMIDE HPD, AZI2, HDHD5 APP 3918/4885CYP4F2 2523/4885CYP4A11 2123/4885
US-12398100-B2 Methods and intermediates for preparing hydrochloride salt of 5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide HPD, AZI2, HDHD5 APP 3918/4885CYP4F2 2523/4885CYP4A11 2123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.