Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 14/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25252014 | 1.00 | MELK (0.37) | MELKOPRK1ALDH1A3ALDH1A1AOC3 | |
| SCHEMBL25211358 | 0.88 | EGFR (0.35) | OPRK1ALDH1A3ALDH1A1AOC3 | |
| SCHEMBL25215056 | 0.88 | SMN1; SMN2 (0.39) | OPRK1ALDH1A3ALDH1A1AOC3 | |
| SCHEMBL25244803 | 0.87 | AOC3 (0.39) | MELKOPRK1AOC3 | |
| SCHEMBL31533250 | 0.84 | OPRK1 (0.38) | OPRK1ALDH1A3ALDH1A1AOC3 | |
| SCHEMBL25262043 | 0.84 | OPRK1 (0.38) | OPRK1ALDH1A3ALDH1A1AOC3 | |
| SCHEMBL30376152 | 0.81 | AOC3 (0.36) | OPRK1AOC3 | |
| SCHEMBL25241176 | 0.81 | AOC3 (0.36) | OPRK1AOC3 | |
| SCHEMBL29287745 | 0.81 | ALDH1A3 (0.37) | OPRK1ALDH1A3ALDH1A1AOC3 | |
| SCHEMBL22322258 | 0.81 | SIRT2 (0.43) | MELKOPRK1ALDH1A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423708-B | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2025-04-22 | — | — | CN | disclosed |