Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31371865 | 0.85 | TRPV4 (0.36) | TRPV4 | |
| SCHEMBL31287351 | 0.81 | ADORA2A (0.37) | — | |
| SCHEMBL31535947 | 0.79 | TRPV4 (0.34) | TRPV4 | |
| SCHEMBL1629238 | 0.79 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL30881834 | 0.77 | KCNN4 (0.31) | — | |
| SCHEMBL31336126 | 0.77 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL26076211 | 0.77 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL974652 | 0.77 | TRPV4 (0.58) | TRPV4 | |
| SCHEMBL25329568 | 0.76 | EPAS1 (0.36) | — | |
| SCHEMBL25565636 | 0.76 | TRPV4 (0.37) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | Isosterix, Inc. | 2025-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | MNAT1, SUGT1, ACAT2 | TRPV4 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.