SCHEMBL31537668

SCHEMBL31537668

CCn1cc(C(F)(F)F)nc1-c1ccc(COc2nc(Cl)nc3ncccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ USP1 O94782 20/20 0.44
▸ WDR48 Q8TAF3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31537624 0.91 USP1 (0.38) USP1WDR48
SCHEMBL31537586 0.88 DGAT1 (0.52) USP1
SCHEMBL31138457 0.87 USP1 (0.41) USP1
SCHEMBL31138747 0.85 USP1 (0.34) USP1
SCHEMBL31138542 0.84 USP1 (0.41) USP1
SCHEMBL31254861 0.80 USP1 (0.48) USP1WDR48
SCHEMBL31155944 0.78 USP1 (0.50) USP1WDR48
SCHEMBL31138428 0.76 USP1 (0.37) USP1
SCHEMBL31537682 0.76 USP1 (0.45) USP1
SCHEMBL31138739 0.76 USP1 (0.43) USP1WDR48

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096494-A1 UBIQUITIN SPECIFIC PROCESSING PROTEASE 1 (USP1) COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
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