Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.49 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.39 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538786 | 0.98 | GPR84 (0.57) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL30642393 | 0.85 | GPR84 (0.49) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL31744906 | 0.85 | GPR84 (0.49) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL10666089 | 0.77 | GGPS1 (0.50) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL8360107 | 0.77 | GGPS1 (0.53) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL9797098 | 0.77 | GGPS1 (0.56) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL28036377 | 0.77 | GGPS1 (0.53) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL5755912 | 0.77 | GGPS1 (0.53) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL25767061 | 0.77 | GGPS1 (0.53) | GPR84GGPS1FDPSNPSR1DRD4 | |
| SCHEMBL10146037 | 0.76 | GPR84 (0.49) | GPR84GGPS1FDPSNPSR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025091123-A1 | MESOIONIC CARBENES | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2025-05-08 | — | — | WO | disclosed |