SCHEMBL31744906

SCHEMBL31744906

Brc1ccc(Cc2cnc3ccccn23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPR84 Q9NQS5 1/20 0.49
▸ KDM4E B2RXH2 5/20 0.47
▸ RAB9A P51151 4/20 0.47
▸ GGPS1 O95749 1/20 0.46
▸ FDPS P14324 1/20 0.46
▸ NPC1 O15118 3/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ HDAC1 Q13547 1/20 0.42
▸ FLT3 P36888 1/20 0.42
▸ DRD4 P21917 1/20 0.41
▸ DRD3 P35462 1/20 0.41
▸ MAPT P10636 1/20 0.40
▸ NPSR1 Q6W5P4 2/20 0.40
▸ MIF P14174 1/20 0.39
▸ PLAU P00749 2/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ CSF1R P07333 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ ADORA3 P0DMS8 1/20 0.37
▸ EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31538786 0.87 GPR84 (0.57) GPR84KDM4ERAB9AGGPS1FDPS
Bromide SCHEMBL31538776 0.85 GPR84 (0.56) GPR84KDM4ERAB9AGGPS1FDPS
SCHEMBL30642393 0.84 GPR84 (0.49) GPR84KDM4EGGPS1FDPSHDAC1
SCHEMBL18766645 0.78 PRNP (0.46) GPR84RAB9ANPC1FLT3MAPT
SCHEMBL7222910 0.73 GGPS1 (0.50) GPR84KDM4ERAB9AGGPS1FDPS
SCHEMBL18265799 0.73 GGPS1 (0.53) GPR84KDM4ERAB9AGGPS1FDPS
SCHEMBL8360107 0.73 GGPS1 (0.53) GPR84KDM4ERAB9AGGPS1FDPS
SCHEMBL2017760 0.73 GGPS1 (0.53) GPR84KDM4ERAB9AGGPS1FDPS
SCHEMBL5755912 0.73 GGPS1 (0.53) GPR84KDM4ERAB9AGGPS1FDPS
SCHEMBL9797098 0.73 GGPS1 (0.56) GPR84KDM4ERAB9AGGPS1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US claimed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US disclosed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 GPR84 4183/4885KDM4E 4133/4885RAB9A 1795/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 GPR84 4183/4885KDM4E 4133/4885RAB9A 1795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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