Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.33 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.33 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24481344 | 0.90 | GBA1 (0.37) | GNAO1TSHRCYP1A2CYP2D6ALOX15 | |
| SCHEMBL27344671 | 0.89 | TSHR (0.34) | TLR9TLR8TLR7SLC6A1GABRA5 | |
| SCHEMBL25026748 | 0.86 | TSHR (0.32) | TSHRCYP1A2CYP2D6ALOX15MEN1 | |
| SCHEMBL24833092 | 0.84 | SLC6A1 (0.37) | TLR9TLR8TLR7SLC6A1GABRA5 | |
| SCHEMBL23484813 | 0.84 | SLC6A1 (0.37) | TLR9TLR8TLR7SLC6A1GABRA5 | |
| SCHEMBL2110725 | 0.84 | SLC6A1 (0.37) | TLR9TLR8TLR7SLC6A1GABRA5 | |
| SCHEMBL25026759 | 0.84 | CYP2D6 (0.35) | TLR9TLR8TLR7TSHRCYP2D6 | |
| SCHEMBL24694609 | 0.83 | SLC6A1 (0.35) | TLR9TLR8TLR7SLC6A1GABRA5 | |
| SCHEMBL24925605 | 0.81 | SLC6A1 (0.35) | TLR9TLR8TLR7SLC6A1GABRA5 | |
| SCHEMBL25001356 | 0.81 | SIGMAR1 (0.41) | CYP1A2CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684317-A | Macrocyclic compound and application thereof | 郑州德迈药业有限公司 | 2025-03-25 | — | — | CN | disclosed |