SCHEMBL31540145

SCHEMBL31540145

Ic1ccc2c(c1)oc1c(I)cccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.40
AHR P35869 5/20 0.35
MAOA P21397 3/20 0.35
ALOX5 P09917 2/20 0.35
MAPT P10636 3/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HPGD P15428 1/20 0.34
PTPRF P10586 2/20 0.33
PTPN2 P17706 2/20 0.33
PTPN1 P18031 2/20 0.33
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
RXFP1 Q9HBX9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31540146 1.00 DYRK1A (0.40) DYRK1AAHRMAOAALOX5MAPT
SCHEMBL23404629 1.00 DYRK1A (0.40) DYRK1AAHRMAOAALOX5MAPT
SCHEMBL12610225 0.85 PTPRF (0.41) AHRMAOAALOX5MAPTKDM4E
SCHEMBL20829181 0.82 MAOB (0.39) DYRK1AAHRMAOAMAPTALDH1A1
SCHEMBL25493112 0.82 LOXL2 (0.39) DYRK1AAHRMAOAALOX5MAPT
SCHEMBL23407543 0.82 DYRK1A (0.38) DYRK1AAHRMAOAALOX5MAPT
SCHEMBL22505857 0.82 DYRK1A (0.49) DYRK1AAHRMAOAALOX5MAPT
SCHEMBL2521186 0.80 ALOX5 (0.46) AHRMAOAALOX5MAPTKDM4E
SCHEMBL22919940 0.80 ALOX5 (0.40) DYRK1AAHRALOX5MAPTKDM4E
SCHEMBL30382274 0.79 KMT2A (0.45) DYRK1AMAPTKDM4EALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979597-B Heterocyclic compound and organic light-emitting device including the same 三星电子株式会社 2025-05-13 CN disclosed