Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | RET | P07949 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | USP2 | O75604 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31642145 | 0.87 | ALDH1A1 (0.38) | ALDH1A1HSD17B10CYP1A2HPGDRET | |
| SCHEMBL723901 | 0.80 | PLD1 (0.49) | ALDH1A1HSD17B10CYP1A2HPGDRET | |
| SCHEMBL29516634 | 0.80 | PLD1 (0.49) | ALDH1A1HSD17B10CYP1A2HPGDRET | |
| SCHEMBL31541401 | 0.78 | ACVR1 (0.36) | ALDH1A1HSD17B10CYP1A2HPGD | |
| SCHEMBL26100489 | 0.75 | CHRNB2 (0.44) | — | |
| SCHEMBL16430513 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CYP1A2HPGDRET | |
| SCHEMBL16431015 | 0.72 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP1A2HPGDRET | |
| SCHEMBL676085 | 0.72 | UBE2T (0.51) | ALDH1A1HSD17B10HPGDSMN1; SMN2MEN1 | |
| SCHEMBL29377204 | 0.72 | UBE2T (0.51) | ALDH1A1HSD17B10HPGDSMN1; SMN2MEN1 | |
| SCHEMBL29712225 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1HSD17B10CYP1A2HPGDRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061029-A1 | FGFR INHIBITORS AND METHODS OF USE THEREOF | 3H PHARMACEUTICALS CO., LTD. (CN) | 2025-03-27 | — | — | WO | disclosed |