Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 5/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.38 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 3/20 | 0.37 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154147 | 1.00 | KLKB1 (0.41) | KLKB1PDPK1NAMPTPSMB5PSMB1 | |
| SCHEMBL1432258 | 0.92 | KLKB1 (0.42) | KLKB1PDPK1NAMPTPSMB5PSMB1 | |
| SCHEMBL3143443 | 0.92 | KLKB1 (0.42) | KLKB1PDPK1NAMPTPSMB5PSMB1 | |
| SCHEMBL3149906 | 0.92 | KLKB1 (0.42) | KLKB1PDPK1NAMPTPSMB5PSMB1 | |
| SCHEMBL3148337 | 0.91 | KLKB1 (0.51) | KLKB1PSMB5PSMB1PSMB2MASP2 | |
| SCHEMBL1432378 | 0.91 | KLKB1 (0.51) | KLKB1PSMB5PSMB1PSMB2MASP2 | |
| SCHEMBL3141370 | 0.90 | KLKB1 (0.40) | KLKB1PDPK1NAMPTPSMB5PSMB1 | |
| SCHEMBL3141334 | 0.90 | KLKB1 (0.40) | KLKB1PDPK1NAMPTPSMB5PSMB1 | |
| SCHEMBL3148388 | 0.89 | KLKB1 (0.42) | KLKB1PDPK1NAMPTPSMB5PSMB1 | |
| SCHEMBL3148409 | 0.89 | KLKB1 (0.42) | KLKB1PDPK1NAMPTPSMB5PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | VANTIA LIMITED (GB) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076015-A1 | Aminopyridine Derivatives | CHRM1, ARG1, ARG2 | KLKB1 3491/4885PDPK1 1972/4885NAMPT 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.