Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31541783 | 0.84 | KDM4E (0.46) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL31541820 | 0.84 | ALDH1A1 (0.44) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL31541780 | 0.84 | KDM4E (0.39) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL31541836 | 0.75 | ALDH1A1 (0.53) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL26604442 | 0.75 | KDM4E (0.46) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL30662910 | 0.75 | KDM4E (0.46) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL31541784 | 0.72 | ALDH1A1 (0.46) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL31541765 | 0.71 | KDM4E (0.39) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL26604506 | 0.70 | ALDH1A1 (0.53) | KMT2AKDM4EMEN1ALDH1A1USP2 | |
| SCHEMBL23455613 | 0.69 | ALDH1A1 (0.58) | KMT2AKDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090809-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2025-05-01 | — | — | WO | disclosed |