Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31541820 | 0.85 | ALDH1A1 (0.44) | KDM4EPKMLMNAMEN1USP2 | |
| SCHEMBL31541783 | 0.72 | KDM4E (0.46) | KDM4EPKMLMNAMEN1USP2 | |
| SCHEMBL31541775 | 0.71 | KMT2A (0.43) | KDM4EPKMLMNAMEN1USP2 | |
| SCHEMBL26696226 | 0.70 | KDM4E (0.49) | KDM4EMTORCNR2LMNAALDH1A1 | |
| SCHEMBL30067156 | 0.70 | KEAP1 (0.46) | KDM4EKEAP1NFE2L2LMNAALDH1A1 | |
| SCHEMBL30232992 | 0.69 | KEAP1 (0.48) | KDM4EPKMKEAP1NFE2L2LMNA | |
| SCHEMBL535587 | 0.69 | KEAP1 (0.48) | KDM4EPKMKEAP1NFE2L2LMNA | |
| SCHEMBL3407486 | 0.68 | HRH4 (0.44) | KDM4ECNR2LMNAMEN1KMT2A | |
| Potassium SCHEMBL1843363 | 0.68 | KEAP1 (0.47) | KDM4EPKMKEAP1NFE2L2LMNA | |
| SCHEMBL26040461 | 0.66 | ALDH1A1 (0.55) | KDM4EKEAP1NFE2L2DHODHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090809-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2025-05-01 | — | — | WO | disclosed |