SCHEMBL3154180

SCHEMBL3154180

CC1[C]=C(C23CC4CC(CC(C4)C2)C3)C=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
LMNA P02545 5/20 0.38
MAPT P10636 2/20 0.33
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GRIN2D O15399 3/20 0.32
GRIN3B O60391 3/20 0.32
GRIN1 Q05586 3/20 0.32
GRIN2A Q12879 3/20 0.32
GRIN2B Q13224 3/20 0.32
GRIN2C Q14957 3/20 0.32
GRIN3A Q8TCU5 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
GFER P55789 1/20 0.32
USP2 O75604 1/20 0.32
THRB P10828 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3162672 0.65 ALDH1A1 (0.35) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL3158935 0.64 NPC1 (0.35) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL3154175 0.63 ALDH1A1 (0.37) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL28889763 0.63 ALDH1A1 (0.40) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL28141032 0.60 LMNA (0.41) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL2763437 0.58 LMNA (0.77) ALDH1A1LMNAMAPTSMN1; SMN2GRIN2D
SCHEMBL20603895 0.58 LMNA (0.40) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL2015810 0.57 TSHR (0.42) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL28299622 0.57 LMNA (0.43) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL21496130 0.56 ALDH1A1 (0.47) ALDH1A1LMNAMAPTTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1985637-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-03-03 EP disclosed
EP-1985638-B1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization MITSUI CHEMICALS INC (JP) 2010-02-17 EP disclosed
EP-1614699-B9 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2009-12-16 EP disclosed
EP-1988104-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-11-05 EP disclosed
EP-1985637-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1985638-A1 Propylene copolymer, polypropylene composition, use thereof, transition metal compounds, and catalysts for olefin polymerization Mitsui Chemicals, Inc. (JP) 2008-10-29 EP disclosed
EP-1614699-B1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION MITSUI CHEMICALS INC (JP) 2008-10-15 EP disclosed
EP-1614699-A1 PROPYLENE COPOLYMER, POLYPROPYLENE COMPOSITION, USE THEREOF, TRANSITION METAL COMPOUNDS, AND CATALYSTS FOR OLEFIN POLYMERIZATION Mitsui Chemicals, Inc. (JP) 2006-01-11 EP disclosed