Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31339602 | 0.91 | HSD17B10 (0.35) | SMN1; SMN2OPRK1HSD17B10HPGDALDH1A1 | |
| SCHEMBL30720464 | 0.79 | OPRK1 (0.39) | SMN1; SMN2OPRK1IRAK4HTR3ACNR2 | |
| SCHEMBL30720572 | 0.77 | KDM4E (0.36) | TP53HPGDALDH1A1BRD4TSHR | |
| SCHEMBL27186169 | 0.77 | OPRK1 (0.42) | SMN1; SMN2OPRK1HSD17B10HPGDALDH1A1 | |
| SCHEMBL27186210 | 0.75 | IRAK4 (0.35) | SMN1; SMN2OPRK1TP53ALDH1A1IRAK4 | |
| SCHEMBL25431879 | 0.73 | CA12 (0.38) | SMN1; SMN2OPRK1ALDH1A1IRAK4CNR2 | |
| SCHEMBL26053358 | 0.73 | OPRK1 (0.38) | OPRK1HSD17B10HPGDALDH1A1ALOX15 | |
| SCHEMBL27186174 | 0.72 | BRD9 (0.40) | TP53IRAK4HTR3ABRD4 | |
| SCHEMBL25433261 | 0.72 | BAZ2B (0.39) | OPRK1TP53HSD17B10HPGDALDH1A1 | |
| SCHEMBL27186173 | 0.72 | ALDH1A1 (0.45) | OPRK1HSD17B10HPGDALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025090809-A1 | MACROCYCLIC HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2025-05-01 | — | — | WO | disclosed |