Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542077 | 0.87 | ALDH1A1 (0.57) | ALDH1A1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL31542055 | 0.86 | NPC1 (0.70) | ALDH1A1KMT2AKDM4EHPGDNPC1 | |
| SCHEMBL31542064 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL31542049 | 0.81 | NPC1 (0.51) | ALDH1A1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL31542057 | 0.80 | HDAC6 (0.60) | ALDH1A1KMT2ACYP2C9CYP2C19NPC1 | |
| SCHEMBL31542069 | 0.79 | ALDH1A1 (0.75) | ALDH1A1KMT2ACYP2C9CYP2C19LMNA | |
| SCHEMBL31542070 | 0.78 | HDAC6 (0.62) | ALDH1A1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL31542050 | 0.78 | HDAC6 (0.53) | ALDH1A1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL31542054 | 0.77 | HDAC6 (0.50) | ALDH1A1KMT2ACYP2C9CYP2C19NPC1 | |
| SCHEMBL4393532 | 0.76 | ALDH1A1 (0.63) | ALDH1A1KMT2ACYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622964-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | Gilva Therapeutics Co., Ltd. (TW) | 2025-10-01 | — | — | EP | claimed |
| WO-2025085669-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | GILVA THERAPEUTICS CO., LTD. (CN) | 2025-04-24 | — | — | WO | claimed |
| EP-4622964-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | Gilva Therapeutics Co., Ltd. (TW) | 2025-10-01 | — | — | EP | disclosed |
| WO-2025085669-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | GILVA THERAPEUTICS CO., LTD. (CN) | 2025-04-24 | — | — | WO | disclosed |