Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.57 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542055 | 0.92 | NPC1 (0.70) | ALDH1A1NPC1RAB9AHDAC6KMT2A | |
| SCHEMBL31542069 | 0.87 | ALDH1A1 (0.75) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL31542082 | 0.87 | POLB (0.63) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL31542068 | 0.85 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9AHDAC6KMT2A | |
| SCHEMBL31542049 | 0.81 | NPC1 (0.51) | ALDH1A1NPC1RAB9AHDAC6PDE10A | |
| SCHEMBL7018781 | 0.80 | ALDH1A1 (0.60) | ALDH1A1NPC1RAB9APDE10AKMT2A | |
| SCHEMBL31542057 | 0.80 | HDAC6 (0.60) | ALDH1A1NPC1RAB9AHDAC6KMT2A | |
| SCHEMBL31542070 | 0.78 | HDAC6 (0.62) | ALDH1A1NPC1RAB9AHDAC6KMT2A | |
| SCHEMBL31542050 | 0.78 | HDAC6 (0.53) | ALDH1A1NPC1RAB9AHDAC6KMT2A | |
| SCHEMBL31542054 | 0.77 | HDAC6 (0.50) | ALDH1A1NPC1RAB9AHDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622964-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | Gilva Therapeutics Co., Ltd. (TW) | 2025-10-01 | — | — | EP | claimed |
| WO-2025085669-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | GILVA THERAPEUTICS CO., LTD. (CN) | 2025-04-24 | — | — | WO | claimed |
| EP-4622964-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | Gilva Therapeutics Co., Ltd. (TW) | 2025-10-01 | — | — | EP | disclosed |
| WO-2025085669-A1 | QUINAZOLINONE DERIVATIVES FOR HDAC INHIBITION | GILVA THERAPEUTICS CO., LTD. (CN) | 2025-04-24 | — | — | WO | disclosed |