Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542289 | 0.86 | GRM1 (0.41) | ELANEKDM1AGRM5GRM1PDK4 | |
| SCHEMBL31542332 | 0.82 | EGLN2 (0.44) | GPR119 | |
| SCHEMBL31542350 | 0.81 | GPR119 (0.40) | GPR119 | |
| SCHEMBL26548555 | 0.77 | MAPT (0.37) | BRD4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31542292 | 0.76 | NOTCH1 (0.36) | GPR119 | |
| SCHEMBL31425849 | 0.76 | GRM1 (0.47) | BRD4GRM5GRM1KITPDK4 | |
| SCHEMBL31542279 | 0.75 | BRPF1 (0.35) | BRD4GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL31542300 | 0.75 | GPR119 (0.41) | GPR119 | |
| SCHEMBL31542329 | 0.75 | ALK (0.35) | GPR119 | |
| SCHEMBL26548588 | 0.74 | BRPF1 (0.39) | BRD4KDM1AGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062330-A1 | HETEROCYCLIC COMPOUNDS AS CBP SELECTIVE DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-03-27 | — | — | WO | disclosed |