Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 3/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27030353 | 0.89 | KDM4E (0.68) | L3MBTL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL22468805 | 0.85 | KDM4E (0.71) | L3MBTL1KDM4EALDH1A1HTTPLA2G2A | |
| SCHEMBL30758183 | 0.84 | L3MBTL1 (0.72) | L3MBTL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL16832230 | 0.84 | L3MBTL1 (0.72) | L3MBTL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL31266680 | 0.83 | DHODH (0.62) | L3MBTL1KDM4EALDH1A1HTTMAPT | |
| SCHEMBL11894679 | 0.83 | KDM4E (0.68) | L3MBTL1KDM4EALDH1A1HTTPLA2G2A | |
| SCHEMBL28840836 | 0.83 | L3MBTL1 (0.71) | L3MBTL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL20472457 | 0.83 | KDM4E (0.68) | L3MBTL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL2348562 | 0.82 | ALDH1A1 (0.50) | L3MBTL1KDM4EALDH1A1SMN1; SMN2HTT | |
| SCHEMBL30365659 | 0.81 | KDM4E (1.00) | KDM4EALDH1A1HTTMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025098450-A1 | PRMT5 INHIBITOR AND PREPARATION METHOD THEREFOR | 北京泰德制药股份有限公司 | 2025-05-15 | — | — | WO | disclosed |