SCHEMBL31546220

SCHEMBL31546220

O=C(Nc1cccc2c1oc1ccccc12)c1ccc(NS(=O)(=O)CCO)cc1N1CCC2(CC1)CC2

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KIF18A Q8NI77 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546217 1.00 KIF18A (0.66) KIF18A
SCHEMBL31613832 0.87 KIF18A (0.72) KIF18A
SCHEMBL31613836 0.84 KIF18A (0.70) KIF18A
SCHEMBL31018687 0.81 KIF18A (0.66) KIF18A
SCHEMBL31613839 0.81 KIF18A (0.68) KIF18A
SCHEMBL31613829 0.80 KIF18A (0.67) KIF18A
SCHEMBL31613830 0.80 KIF18A (0.72) KIF18A
SCHEMBL31694746 0.80 KIF18A (0.60) KIF18A
SCHEMBL22964485 0.80 KIF18A (1.00) KIF18A
SCHEMBL30842193 0.80 KIF18A (0.69) KIF18A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119731163-A KIF18A inhibitor compound, pharmaceutical composition, preparation method and application thereof 长春金赛药业有限责任公司 2025-03-28 — — CN disclosed
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