Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.41 |
| ▸ | HTR2A | P28223 | 7/20 | 0.41 |
| ▸ | HTR2C | P28335 | 7/20 | 0.41 |
| ▸ | HTR2B | P41595 | 7/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 7/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842141 | 0.93 | PARP10 (0.46) | PARP10PARP11CDK5PIM1CSNK1A1 | |
| SCHEMBL4317715 | 0.84 | PARP10 (0.50) | PARP10PARP11CDK5PIM1CSNK1A1 | |
| SCHEMBL23980585 | 0.81 | PARP10 (0.47) | PARP10PARP11CDK5PIM1CSNK1A1 | |
| SCHEMBL28502513 | 0.75 | PARP10 (0.45) | PARP10PARP11CDK5PIM1CSNK1A1 | |
| SCHEMBL7923840 | 0.74 | PARP10 (0.42) | PARP10PARP11CDK5PIM1CSNK1A1 | |
| SCHEMBL19041482 | 0.73 | LDHA (0.35) | PARP10PARP11CDK5PIM1CSNK1A1 | |
| SCHEMBL7052870 | 0.72 | PARP10 (0.58) | PARP10PARP11CDK5PIM1CSNK1A1 | |
| SCHEMBL8779031 | 0.72 | SIGMAR1 (0.40) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL23980062 | 0.72 | SMN1; SMN2 (0.52) | PARP10PARP11CDK5PIM1CSNK1A1 | |
| SCHEMBL18440344 | 0.71 | SIGMAR1 (0.41) | PARP10PARP11SIGMAR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4567032-A1 | KIF18A INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR AND USE THEREOF | Changchun Genescience Pharmaceutical Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| CN-119731163-A | KIF18A inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2025-03-28 | — | — | CN | disclosed |