SCHEMBL31546461

SCHEMBL31546461

C#Cc1ccc(CN2CCC(CNC(=O)C3CCN(c4nc(-c5ccc(OC)cc5)no4)CC3)C2)cc1

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.57
▸ MEN1 O00255 4/20 0.57
▸ KMT2A Q03164 4/20 0.57
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ POLB P06746 2/20 0.51
▸ MAPT P10636 1/20 0.51
▸ TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25437981 0.92 LMNA (0.59) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL30585033 0.92 LMNA (0.59) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL31546344 0.91 MEN1 (0.55) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL31546367 0.91 POLB (0.60) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL31546397 0.91 MEN1 (0.60) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL31546325 0.90 MEN1 (0.59) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL31667355 0.89 LMNA (0.58) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL31546420 0.87 MEN1 (0.57) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL31546360 0.87 MEN1 (0.57) LMNAMEN1KMT2ASMN1; SMN2POLB
SCHEMBL30584881 0.87 MEN1 (0.59) LMNAMEN1KMT2ASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 LMNA 1344/4885MEN1 1569/4885KMT2A 1404/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 LMNA 1344/4885MEN1 1569/4885KMT2A 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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