SCHEMBL31667355

SCHEMBL31667355

COc1ccc(-c2noc(N3CCC(C(=O)NCC4CCN(Cc5ccc(C)nc5)C4)CC3)n2)cc1

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.58
▸ MEN1 O00255 4/20 0.57
▸ KMT2A Q03164 4/20 0.57
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ MAPT P10636 2/20 0.53
▸ POLB P06746 1/20 0.49
▸ TSHR P16473 1/20 0.49
▸ KDM4E B2RXH2 1/20 0.49
▸ ALDH1A1 P00352 1/20 0.49
▸ TP53 P04637 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL30584873 0.97 LMNA (0.55) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL25437981 0.92 LMNA (0.59) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL30584916 0.91 MEN1 (0.56) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL25437574 0.91 MEN1 (0.56) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL30585033 0.91 LMNA (0.59) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL31546367 0.90 POLB (0.60) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL31546397 0.90 MEN1 (0.60) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL31546325 0.89 MEN1 (0.59) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL31546419 0.89 MEN1 (0.55) LMNAMEN1KMT2ASMN1; SMN2MAPT
SCHEMBL31546461 0.89 LMNA (0.57) LMNAMEN1KMT2ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP claimed
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 — — EP disclosed
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