Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31546603 | 1.00 | ALDH1A1 (0.62) | ALDH1A1GAAPKMLMNAPOLB | |
| SCHEMBL31546641 | 0.84 | PPARG (0.52) | ALDH1A1GAALMNAHPGDHSD17B10 | |
| SCHEMBL13761448 | 0.84 | HTT (0.50) | ALDH1A1GAAPKMLMNAPOLB | |
| SCHEMBL10604781 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GAAPKMLMNAPOLB | |
| SCHEMBL10604775 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GAAPKMLMNAPOLB | |
| SCHEMBL7046881 | 0.82 | MAPT (0.53) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL31546602 | 0.80 | L3MBTL1 (0.54) | ALDH1A1GAAPKMLMNAPOLB | |
| SCHEMBL10763115 | 0.79 | NPC1 (0.65) | ALDH1A1GAALMNAPOLBSMN1; SMN2 | |
| SCHEMBL10763104 | 0.79 | NPC1 (0.65) | ALDH1A1GAALMNAPOLBSMN1; SMN2 | |
| SCHEMBL10768107 | 0.79 | NPC1 (0.65) | ALDH1A1GAALMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120000651-A | Application of beta-carboline compounds in preparation of medicines for preventing and/or treating acute lung injury | 中国人民解放军北部战区总医院 | 2025-05-16 | — | — | CN | disclosed |
| CN-119899184-A | Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease | 中国人民解放军北部战区总医院 | 2025-04-29 | — | — | CN | disclosed |