SCHEMBL31546708

SCHEMBL31546708

CCOc1cccc(-c2cn(-c3ccc4c(c3)C(=O)N(C3CCC(=O)NC3=O)C4)nn2)n1

nearest known ligand 0.47

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 17/20 0.47
▸ IKZF2 Q9UKS7 2/20 0.45
▸ IKZF1 Q13422 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546892 0.94 IKZF2 (0.50) CRBNIKZF2IKZF1
SCHEMBL31546867 0.91 CRBN (0.48) CRBN
SCHEMBL31546731 0.88 CRBN (0.47) CRBN
SCHEMBL31546752 0.86 CRBN (0.51) CRBNIKZF2
SCHEMBL31546827 0.85 CRBN (0.48) CRBNIKZF2IKZF1
SCHEMBL31546802 0.84 CRBN (0.48) CRBNIKZF2IKZF1
SCHEMBL31546720 0.83 IKZF1 (0.58) CRBNIKZF2IKZF1
SCHEMBL31546805 0.81 CRBN (0.47) CRBNIKZF2IKZF1
SCHEMBL31546837 0.81 CRBN (0.47) CRBNIKZF2IKZF1
SCHEMBL31546883 0.81 CRBN (0.56) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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