SCHEMBL31546752

SCHEMBL31546752

CCOc1ccccc1-c1cn(-c2ccc3c(c2)C(=O)N(C2CCC(=O)NC2=O)C3)nn1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 18/20 0.51
▸ DDB1 Q16531 1/20 0.49
▸ IKZF3 Q9UKT9 2/20 0.46
▸ IKZF2 Q9UKS7 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546870 0.94 CRBN (0.51) CRBNDDB1IKZF3IKZF2
SCHEMBL31546714 0.90 CRBN (0.52) CRBNIKZF3
SCHEMBL31546883 0.87 CRBN (0.56) CRBN
SCHEMBL31546708 0.86 CRBN (0.47) CRBNIKZF2
SCHEMBL31546865 0.85 CRBN (0.53) CRBNIKZF3IKZF2
SCHEMBL31546725 0.84 CRBN (0.48) CRBNIKZF2
SCHEMBL31546743 0.84 CRBN (0.52) CRBNIKZF3IKZF2
SCHEMBL31546851 0.80 CRBN (0.56) CRBNIKZF2
SCHEMBL31546867 0.79 CRBN (0.48) CRBN
SCHEMBL31546770 0.79 CRBN (0.58) CRBNIKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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