SCHEMBL31546802

SCHEMBL31546802

O=C1CCC(N2Cc3cc(-n4cc(-c5cccc(OC6CC6)n5)nn4)ccc3C2=O)C(=O)N1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 9/20 0.48
▸ IKZF1 Q13422 1/20 0.45
▸ IKZF2 Q9UKS7 10/20 0.44
▸ CSNK1A1 P48729 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546805 0.97 CRBN (0.47) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL31546867 0.94 CRBN (0.48) CRBN
SCHEMBL31546827 0.91 CRBN (0.48) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL31546892 0.91 IKZF2 (0.50) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL31546837 0.89 CRBN (0.47) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL31546720 0.89 IKZF1 (0.58) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL31546743 0.85 CRBN (0.52) CRBNIKZF1IKZF2CSNK1A1
SCHEMBL31546708 0.84 CRBN (0.47) CRBNIKZF1IKZF2
SCHEMBL31546855 0.83 IKZF2 (0.49) CRBNIKZF1IKZF2
SCHEMBL31546731 0.83 CRBN (0.47) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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