SCHEMBL31546747

SCHEMBL31546747

CC(C)(C)OC(=O)N1CC(Cn2cc(-c3cn(-c4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)nn3)cn2)C1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ IKZF2 Q9UKS7 12/20 0.41
▸ CRBN Q96SW2 7/20 0.41
▸ CSNK1A1 P48729 3/20 0.38
▸ GSPT1 P15170 1/20 0.37
▸ SALL4 Q9UJQ4 1/20 0.37
▸ IKZF3 Q9UKT9 1/20 0.37
▸ ESR1 P03372 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546718 0.89 CRBN (0.42) IKZF2CRBNCSNK1A1GSPT1SALL4
SCHEMBL20231897 0.79 CRBN (0.53) IKZF2CRBNCSNK1A1GSPT1IKZF3
SCHEMBL30906200 0.78 CRBN (0.48) IKZF2CRBNCSNK1A1ESR1
SCHEMBL30906241 0.77 CRBN (0.47) IKZF2CRBNCSNK1A1GSPT1IKZF3
SCHEMBL30906282 0.77 CRBN (0.52) IKZF2CRBNESR1
SCHEMBL30942475 0.76 IKZF2 (0.51) IKZF2CRBNCSNK1A1GSPT1IKZF3
SCHEMBL20235032 0.76 CRBN (0.49) IKZF2CRBNCSNK1A1GSPT1SALL4
SCHEMBL27302318 0.76 IKZF2 (0.51) IKZF2CRBNCSNK1A1GSPT1IKZF3
SCHEMBL25581068 0.76 CRBN (0.54) IKZF2CRBNCSNK1A1GSPT1IKZF3
SCHEMBL31546771 0.76 CRBN (0.48) IKZF2CRBNCSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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