SCHEMBL31546718

SCHEMBL31546718

CC(C)(C)OC(=O)N1CC(n2cc(-c3cn(-c4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)nn3)cn2)C1

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 11/20 0.42
▸ DDB1 Q16531 2/20 0.41
▸ IKZF2 Q9UKS7 8/20 0.40
▸ CSNK1A1 P48729 3/20 0.39
▸ GSPT1 P15170 1/20 0.37
▸ SALL4 Q9UJQ4 1/20 0.37
▸ IKZF3 Q9UKT9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546747 0.89 IKZF2 (0.41) CRBNIKZF2CSNK1A1GSPT1SALL4
SCHEMBL20235032 0.87 CRBN (0.49) CRBNDDB1IKZF2CSNK1A1GSPT1
SCHEMBL31546774 0.84 CRBN (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546771 0.84 CRBN (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31025907 0.79 CRBN (0.47) CRBNDDB1IKZF2CSNK1A1GSPT1
SCHEMBL30985154 0.79 CRBN (0.45) CRBNDDB1IKZF2CSNK1A1GSPT1
SCHEMBL30984814 0.78 CRBN (0.46) CRBNDDB1IKZF2CSNK1A1GSPT1
SCHEMBL24675665 0.78 CRBN (0.51) CRBNDDB1IKZF2CSNK1A1GSPT1
SCHEMBL30942354 0.78 CRBN (0.51) CRBNDDB1IKZF2CSNK1A1GSPT1
SCHEMBL29823049 0.78 CRBN (0.51) CRBNDDB1IKZF2CSNK1A1GSPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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