SCHEMBL31546743

SCHEMBL31546743

O=C1CCC(N2Cc3cc(-n4cc(-c5ccccc5OC5CC5)nn4)ccc3C2=O)C(=O)N1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 9/20 0.52
▸ CSNK1A1 P48729 1/20 0.46
▸ IKZF2 Q9UKS7 10/20 0.45
▸ IKZF3 Q9UKT9 1/20 0.43
▸ IKZF1 Q13422 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546714 0.93 CRBN (0.52) CRBNIKZF3
SCHEMBL31546865 0.91 CRBN (0.53) CRBNCSNK1A1IKZF2IKZF3
SCHEMBL31546870 0.90 CRBN (0.51) CRBNCSNK1A1IKZF2IKZF3
SCHEMBL31546770 0.87 CRBN (0.58) CRBNCSNK1A1IKZF2IKZF1
SCHEMBL31546851 0.86 CRBN (0.56) CRBNCSNK1A1IKZF2
SCHEMBL31546802 0.85 CRBN (0.48) CRBNCSNK1A1IKZF2IKZF1
SCHEMBL31546752 0.84 CRBN (0.51) CRBNIKZF2IKZF3
SCHEMBL31546786 0.84 CRBN (0.48) CRBNCSNK1A1IKZF2
SCHEMBL31546765 0.84 WIZ (0.52) CRBNCSNK1A1IKZF2
SCHEMBL31546810 0.82 IKZF2 (0.49) CRBNCSNK1A1IKZF2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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