SCHEMBL31546687

SCHEMBL31546687

COc1ccc(-c2cn(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nn2)nc1OC

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 11/20 0.48
▸ IKZF2 Q9UKS7 11/20 0.45
▸ WIZ O95785 1/20 0.43
▸ CSNK1A1 P48729 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546742 0.92 CRBN (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546739 0.91 CRBN (0.47) CRBNIKZF2CSNK1A1
SCHEMBL31546827 0.86 CRBN (0.48) CRBNIKZF2CSNK1A1
SCHEMBL31546865 0.86 CRBN (0.53) CRBNIKZF2WIZCSNK1A1
SCHEMBL31546786 0.86 CRBN (0.48) CRBNIKZF2WIZCSNK1A1
SCHEMBL31546808 0.86 CRBN (0.48) CRBNIKZF2WIZ
SCHEMBL31546765 0.85 WIZ (0.52) CRBNIKZF2WIZCSNK1A1
SCHEMBL31546894 0.85 IKZF2 (0.56) CRBNIKZF2WIZCSNK1A1
SCHEMBL31546855 0.85 IKZF2 (0.49) CRBNIKZF2
SCHEMBL31546910 0.84 CRBN (0.51) CRBNIKZF2WIZCSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025076285-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME DELPHIA THERAPEUTICS, INC. (US) 2025-04-10 — — WO disclosed
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