SCHEMBL3154682

SCHEMBL3154682

CC(=O)N(Cl)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.53
ALDH1A1 P00352 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.47
MEN1 O00255 1/20 0.47
CRHBP P24387 1/20 0.47
KMT2A Q03164 1/20 0.47
ATM Q13315 1/20 0.47
CRHR2 Q13324 1/20 0.47
TLR9 Q9NR96 1/20 0.47
CES1 P23141 1/20 0.47
TDP1 Q9NUW8 2/20 0.46
TSHR P16473 2/20 0.46
MAPT P10636 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
PHLPP2 Q6ZVD8 1/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
ACHE P22303 1/20 0.45
HSD17B10 Q99714 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836813 0.83 ALDH1A1 (0.55) MAPK1ALDH1A1L3MBTL1MEN1CRHBP
SCHEMBL11072781 0.83 ALDH1A1 (0.53) MAPK1ALDH1A1L3MBTL1MEN1CRHBP
SCHEMBL12200280 0.82 ALDH1A1 (0.39) MAPK1ALDH1A1KMT2ATDP1TSHR
SCHEMBL27850590 0.81 TSHR (0.53) MAPK1ALDH1A1L3MBTL1MEN1CRHBP
SCHEMBL3159374 0.80 ALDH1A1 (0.54) MAPK1ALDH1A1MEN1KMT2ACES1
SCHEMBL2103568 0.79 MAPK1 (0.55) MAPK1ALDH1A1L3MBTL1MEN1CRHBP
SCHEMBL874309 0.79 MAPK1 (0.55) MAPK1ALDH1A1L3MBTL1MEN1CRHBP
SCHEMBL7035059 0.78 MAPK1 (0.53) MAPK1ALDH1A1L3MBTL1MEN1CRHBP
SCHEMBL9631542 0.78 MAPK1 (0.53) MAPK1ALDH1A1L3MBTL1MEN1CRHBP
SCHEMBL27635231 0.78 MAPK1 (0.53) MAPK1ALDH1A1L3MBTL1MEN1CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1749880-B1 Cleaning compositions and methods RECKITT BENCKISER UK LTD (GB) 2013-04-17 EP disclosed
US-8258092-B2 Cleaning compositions and methods RECKITT BENCKISER (UK) LIMITED (GB) 2012-09-04 US disclosed
CN-1989233-B Improvement of cleaning or relating to cleaning RECKITT BENCKISER UK LTD (GB) 2011-01-12 CN disclosed
EP-2157161-A1 Improvements in or relating to cleaning Reckitt-Benckiser (UK) Limited (GB) 2010-02-24 EP disclosed
US-7638470-B2 Cleaning RECKITT BENCKISER (UK) LIMITED (GB) 2009-12-29 US disclosed
EP-1771537-B1 IMPROVEMENTS IN OR RELATING TO CLEANING RECKITT BENCKISER UK LTD (GB) 2009-12-16 EP disclosed
US-20080230095-A1 Cleaning Compositions and Methods RECKITT BENCKISER (UK) LIMITED (GB) 2008-09-25 US disclosed
US-20070254824-A1 Multicompartment container for a liquid cleaning compound in combination with a solid oxidation catalyst which when in contact with the cleaner causes a reaction to increase its oxidation power, or change its pH, cause gas evolution, or release heat; antisoilants; tough stains; fabrics; surfaces RECKITT BENCKISER (UK) LIMITED (GB) 2007-11-01 US disclosed
CN-1989233-A Liquid cleaning composition, catalyst therefor and methods of cleaning RECKITT BENCKISER UK LTD (GB) 2007-06-27 CN disclosed
EP-1360270-B1 AUTOMATIC DISHWASHING COMPOSITIONS COMPRISING BLOOMING PERFUME AND BASE MASKING INGREDIENTS PROCTER & GAMBLE (US) 2007-05-16 EP disclosed
EP-1360270-A2 AUTOMATIC DISHWASHING COMPOSITIONS COMPRISING BLOOMING PERFUME AND BASE MASKING INGREDIENTS THE PROCTER & GAMBLE COMPANY (US) 2003-11-12 EP disclosed
EP-0888446-B1 TOILET BOWL DETERGENT SYSTEM CONTAINING BLOOMING PERFUME PROCTER & GAMBLE (US) 2003-10-15 EP disclosed
US-20020169091-A1 Automatic dishwashing compositions comprising blooming perfume and base masking ingredients PROCTER & GAMBLE COMPANY, THE 2002-11-14 US disclosed
WO-2002064723-A2 AUTOMATIC DISHWASHING COMPOSITIONS COMPRISING BLOOMING PERFUME AND BASE MASKING INGREDIENTS THE PROCTER & GAMBLE COMPANY (US) 2002-08-22 WO disclosed
US-6143707-A CLEANING AND STAIN REMOVAL AND PROVIDE A POSITIVE SCENT; FOR WASHING KITCHENWARE THE PROCTER & GAMBLE COMPANY (US) 2000-11-07 US disclosed
US-6001789-A BLOCK DETERGENT COMPRISING MOISTURE ACTIVATED ENCAPSULATED PERFUME PARTICLES, SURFACTANT, DETERGENT BUILDER AND SYSTEM FOR PROVIDING CONCENTRATION OF CLEANING COMPOUND TO TOILET WATER THE PROCTER & GAMBLE COMPANY (US) 1999-12-14 US disclosed
EP-0888441-A1 BUILT AUTOMATIC DISHWASHING COMPOSITIONS COMPRISING BLOOMING PERFUME THE PROCTER & GAMBLE COMPANY (US) 1999-01-07 EP disclosed
WO-1997034987-A1 BUILT AUTOMATIC DISHWASHING COMPOSITIONS COMPRISING BLOOMING PERFUME THE PROCTER & GAMBLE COMPANY (US) 1997-09-25 WO disclosed
WO-1997007188-A1 HAND DISHWASHING POWDER WITH CHLORINE BLEACH THE PROCTER & GAMBLE COMPANY (US) 1997-02-27 WO disclosed
EP-0002586-B1 METHOD FOR REMOVING A HALOGENOACETYL PROTECTIVE GROUP FROM A HALOGENOACETYL AMINO COMPOUND Takeda Chemical Industries, Ltd. (JP) 1982-01-20 EP disclosed