SCHEMBL12200280

SCHEMBL12200280

CC(=O)N(Cl)c1ccc(N(Cl)C(C)=O)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
KMT2A Q03164 1/20 0.38
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.35
TSHR P16473 1/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.34
RAB9A P51151 4/20 0.34
POLB P06746 2/20 0.33
NPC1 O15118 2/20 0.33
MAPK1 P28482 1/20 0.33
FSCN1 Q16658 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MT-CO2 P00403 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10863831 0.91 CA2 (0.40) ALDH1A1KMT2AMAPTHPGDTSHR
SCHEMBL3150016 0.91 LMNA (0.46) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL3149268 0.91 LMNA (0.46) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL2724523 0.87 NPSR1 (0.46) ALDH1A1KMT2ASMN1; SMN2TSHRLMNA
SCHEMBL10920659 0.87 HPGD (0.48) ALDH1A1KMT2AMAPTHPGDSMN1; SMN2
SCHEMBL1031452 0.85 ALDH1A1 (0.45) ALDH1A1HPGDSMN1; SMN2TSHRRAB9A
SCHEMBL27388740 0.85 ALDH1A1 (0.39) ALDH1A1KMT2AMAPTSMN1; SMN2TSHR
SCHEMBL7197824 0.84
SCHEMBL9350081 0.83 ALDH1A1 (0.42) ALDH1A1KMT2AMAPTTSHRLMNA
SCHEMBL4873036 0.83 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8034892-B2 Biocidal polymer and process for preparing the same FAR EASTERN NEW CENTURY CORPORATION (TW) 2011-10-11 US disclosed
US-8034892-B2 Biocidal polymer and process for preparing the same FAR EASTERN NEW CENTURY CORPORATION (TW) 2011-10-11 US disclosed
US-20090318659-A1 BIOCIDAL POLYMER AND PROCESS FOR PREPARING THE SAME FAR EASTERN NEW CENTURY CORPORATION (TW) 2009-12-24 US disclosed
US-20090318659-A1 BIOCIDAL POLYMER AND PROCESS FOR PREPARING THE SAME FAR EASTERN NEW CENTURY CORPORATION (TW) 2009-12-24 US disclosed