Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13572996 | 0.73 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL22750831 | 0.73 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL24317084 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL22750826 | 0.68 | — | — | |
| SCHEMBL15934084 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL6958862 | 0.67 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL1494644 | 0.67 | KDM4E (0.35) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL17918659 | 0.67 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL13512799 | 0.67 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL6970737 | 0.67 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072330-A1 | KIT INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2025-04-03 | — | — | WO | disclosed |