Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6958865 | 0.81 | L3MBTL1 (0.37) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL13572996 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL6410626 | 0.73 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL24317084 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL13512799 | 0.69 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL6970737 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL17918659 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL6408814 | 0.67 | ADORA2B (0.32) | ADORA2AADORA2B | |
| SCHEMBL31547056 | 0.67 | KDM4E (0.32) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL15934084 | 0.67 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | claimed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |