Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13572996 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL24317084 | 0.77 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL17918659 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL13512799 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL15934084 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL11327540 | 0.71 | KDM4E (0.37) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL6958862 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL6958865 | 0.69 | L3MBTL1 (0.37) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL21163695 | 0.68 | ADORA2A (0.36) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G | |
| SCHEMBL11458001 | 0.67 | KDM4E (0.34) | KDM4EALDH1A1HPGDHSD17B10APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |