Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30364997 | 0.90 | LMNA (0.44) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL30364650 | 0.87 | LMNA (0.43) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL25149343 | 0.86 | LMNA (0.41) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL30365185 | 0.86 | LMNA (0.41) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL30365013 | 0.85 | LMNA (0.40) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL30364609 | 0.81 | LMNA (0.41) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL30364621 | 0.80 | LMNA (0.48) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL30365111 | 0.80 | LMNA (0.48) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL30364760 | 0.79 | LMNA (0.44) | LMNAMEN1KMT2AJAK2TP53 | |
| SCHEMBL25149477 | 0.78 | BRD4 (0.39) | LMNAMEN1KMT2AJAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025073792-A1 | WRN INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2025-04-10 | — | — | WO | claimed |
| WO-2025073792-A1 | WRN INHIBITORY COMPOUNDS | FORX THERAPEUTICS AG (CH) | 2025-04-10 | — | — | WO | disclosed |