SCHEMBL31547660

SCHEMBL31547660

Cc1cc(B2OC(C)(C)C(C)(C)O2)sc1C

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.33
LIPG Q9Y5X9 7/20 0.33
P2RX7 Q99572 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
DAO P14920 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPK1 P28482 1/20 0.32
USP30 Q70CQ3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL824177 0.82 JAK2 (0.32) LPLLIPGP2RX7
SCHEMBL28519289 0.80 DAO (0.36) LPLLIPGP2RX7DAOMAPK1
SCHEMBL1829293 0.78 LPL (0.35) LPLLIPGP2RX7MAPK1USP30
SCHEMBL31387250 0.78 ESR2 (0.31)
SCHEMBL1830220 0.75 LPL (0.35) LPLLIPGP2RX7MAPK1USP30
SCHEMBL11928934 0.75 LPL (0.31) LPLLIPGP2RX7
SCHEMBL24759504 0.73 ALDH1A1 (0.37) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL28559742 0.73 KDM4E (0.37) KDM4EMEN1ALDH1A1MAPTKMT2A
SCHEMBL13721705 0.73 MAPK1 (0.34) LPLLIPGP2RX7MAPK1USP30
SCHEMBL10053904 0.73 LPL (0.32) LPLLIPGP2RX7MAPK1USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025073792-A1 WRN INHIBITORY COMPOUNDS FORX THERAPEUTICS AG (CH) 2025-04-10 WO disclosed