Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.50 |
| ▸ | ACE | P12821 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PEPD | P12955 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905705 | 0.89 | ACE (0.58) | RENACEKDM4EF2LMNA | |
| SCHEMBL29666480 | 0.88 | ACE (0.57) | RENACEKDM4EF2LMNA | |
| SCHEMBL30315374 | 0.87 | REN (0.51) | RENACEKDM4EF2LMNA | |
| SCHEMBL22638015 | 0.86 | ACE (0.50) | RENACEKDM4EF2LMNA | |
| SCHEMBL22638020 | 0.86 | ACE (0.50) | RENACEKDM4EF2LMNA | |
| SCHEMBL22638018 | 0.86 | ACE (0.50) | RENACEKDM4EF2LMNA | |
| SCHEMBL30800547 | 0.86 | ACE (0.60) | RENACEKDM4EF2LMNA | |
| SCHEMBL30051880 | 0.86 | REN (0.53) | RENACEKDM4EF2LMNA | |
| SCHEMBL29541526 | 0.85 | ITGB3 (0.40) | RENACEF2 | |
| SCHEMBL29630391 | 0.85 | ACE (0.55) | ACELTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068572-A2 | POLYPEPTIDES COMPRISING INTEINS FOR ENGINEERED EVS | EVOX THERAPEUTICS LIMITED (GB) | 2025-04-03 | — | — | WO | disclosed |