Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.43 |
| ▸ | ATXN2 | Q99700 | 5/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31549816 | 0.90 | MGLL (0.42) | ENPP2ATXN2MGLLIDO1FFAR1 | |
| SCHEMBL31549787 | 0.85 | MGLL (0.43) | ENPP2ATXN2MGLLIDO1FFAR1 | |
| SCHEMBL20695464 | 0.80 | MGLL (0.47) | ENPP2ATXN2MGLLIDO1CYP11B1 | |
| SCHEMBL25324545 | 0.79 | ENPP2 (0.41) | ENPP2ATXN2MGLLIDO1LIPG | |
| SCHEMBL19411886 | 0.78 | IDO1 (0.48) | ENPP2ATXN2MGLLIDO1FFAR1 | |
| SCHEMBL30553308 | 0.77 | ENPP2 (0.39) | ENPP2ATXN2MGLLIDO1FFAR1 | |
| SCHEMBL30700056 | 0.77 | MGLL (0.41) | MGLLIDO1FFAR1NAAALIPG | |
| SCHEMBL27246316 | 0.76 | ENPP2 (0.38) | ENPP2ATXN2MGLLIDO1LIPG | |
| SCHEMBL23850577 | 0.76 | ENPP2 (0.43) | ENPP2ATXN2MGLLIDO1FFAR1 | |
| SCHEMBL30700038 | 0.76 | MGLL (0.44) | ENPP2ATXN2MGLLIDO1LIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068347-A1 | NEW HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-04-03 | — | — | WO | disclosed |