SCHEMBL31549989

SCHEMBL31549989

O=C(Cl)C1C(c2cc(Cl)c(F)c(Cl)c2)C1(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
LMNA P02545 3/20 0.36
NPSR1 Q6W5P4 1/20 0.32
SLC9A1 P19634 1/20 0.32
ALDH1A1 P00352 1/20 0.31
RECQL P46063 1/20 0.31
HTT P42858 2/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18144185 0.86 MEN1 (0.39) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL18144182 0.86 MEN1 (0.39) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL18144181 0.86 MEN1 (0.39) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL29243271 0.86 MEN1 (0.33) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL31565732 0.85 MEN1 (0.34) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL30739754 0.85 SLC9A1 (0.37) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL31549990 0.82 MEN1 (0.41) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL30739905 0.82 MEN1 (0.40) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL18146245 0.80 SLC9A1 (0.47) MEN1KMT2ALMNANPSR1SLC9A1
SCHEMBL18146243 0.80 SLC9A1 (0.47) MEN1KMT2ALMNANPSR1SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954676-A Cyclopropionamide substituted benzamide derivative and preparation method and application thereof 山东省联合农药工业有限公司 2025-05-09 CN disclosed