SCHEMBL29243271

SCHEMBL29243271

O=C(Cl)C1C(c2cc(Cl)c(Cl)c(Cl)c2)C1(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
NPSR1 Q6W5P4 1/20 0.33
SLC9A1 P19634 1/20 0.33
ALDH1A1 P00352 2/20 0.33
RECQL P46063 1/20 0.33
HPGD P15428 2/20 0.32
CYP3A4 P08684 2/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 4/20 0.32
LMNA P02545 3/20 0.32
MAPT P10636 2/20 0.32
MAPK1 P28482 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31565732 0.89 MEN1 (0.34) MEN1KMT2ANPSR1SLC9A1LMNA
SCHEMBL31549989 0.86 MEN1 (0.36) MEN1KMT2ANPSR1SLC9A1ALDH1A1
SCHEMBL19442292 0.85 ALDH1A1 (0.38) MEN1KMT2ANPSR1SLC9A1ALDH1A1
SCHEMBL21019043 0.85 ALDH1A1 (0.38) MEN1KMT2ANPSR1SLC9A1ALDH1A1
SCHEMBL20845988 0.85 ALDH1A1 (0.38) MEN1KMT2ANPSR1SLC9A1ALDH1A1
SCHEMBL18143602 0.85 ALDH1A1 (0.38) MEN1KMT2ANPSR1SLC9A1ALDH1A1
SCHEMBL18143828 0.85 ALDH1A1 (0.38) MEN1KMT2ANPSR1SLC9A1ALDH1A1
SCHEMBL18143907 0.85 ALDH1A1 (0.38) MEN1KMT2ANPSR1SLC9A1ALDH1A1
SCHEMBL31565733 0.85 NOTUM (0.31)
SCHEMBL30739670 0.84 SLC9A1 (0.39) MEN1KMT2ANPSR1SLC9A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119954677-A Cyclopropionamide substituted benzamide derivative and preparation method and application thereof 山东省联合农药工业有限公司 2025-05-09 CN disclosed
CN-119954676-A Cyclopropionamide substituted benzamide derivative and preparation method and application thereof 山东省联合农药工业有限公司 2025-05-09 CN disclosed
CN-118063349-A Cyclopropionamide substituted benzamide derivative and preparation method and application thereof 山东省联合农药工业有限公司 2024-05-24 CN disclosed