Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12835616 | 0.85 | MAPT (0.36) | MAPTMAPK1TDP1GAAHTT | |
| SCHEMBL31553067 | 0.76 | ALDH1A1 (0.42) | MAPTPKMTDP1L3MBTL1GRIN2D | |
| SCHEMBL17555458 | 0.76 | ALDH1A1 (0.36) | MAPTPKMTDP1HTTAAK1 | |
| SCHEMBL29071382 | 0.76 | GPR35 (0.37) | MAPTGAAHTTGRIN2DGRIN3B | |
| SCHEMBL29301459 | 0.76 | ALDH1A1 (0.42) | MAPTPKMMAPK1TDP1GAA | |
| SCHEMBL31553071 | 0.73 | GRIN2D (0.35) | MAPTTDP1GAAHTTGRIN2D | |
| SCHEMBL20594965 | 0.72 | ALDH1A1 (0.38) | MAPTPKMMAPK1TDP1GAA | |
| SCHEMBL31553080 | 0.72 | GRIN2D (0.32) | MAPTMAPK1TDP1GRIN2DGRIN3B | |
| SCHEMBL14246396 | 0.69 | MAPT (0.40) | MAPTPKMMAPK1VCPTDP1 | |
| SCHEMBL9000095 | 0.69 | ATM (0.44) | MAPTPKMMAPK1VCPTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025061035-A1 | BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF | 南京再明医药有限公司 | 2025-03-27 | — | — | WO | disclosed |