Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 2/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2752527 | 0.89 | HTR6 (0.41) | PTPN11L3MBTL1CA1CA2CHUK | |
| SCHEMBL31396616 | 0.88 | PTPN11 (0.53) | PTPN11L3MBTL1CA1CA2ENPP3 | |
| SCHEMBL23247251 | 0.85 | L3MBTL1 (0.58) | PTPN11L3MBTL1CA1CA2ENPP3 | |
| SCHEMBL31344454 | 0.84 | PTPN11 (0.50) | PTPN11L3MBTL1ENPP3ENPP1MEN1 | |
| SCHEMBL28769925 | 0.84 | CHUK (0.39) | PTPN11CHUKBRD4BMPR1BKDR | |
| SCHEMBL8443781 | 0.83 | BRD4 (0.44) | PTPN11L3MBTL1CA1CA2CHUK | |
| SCHEMBL31396508 | 0.83 | PTPN11 (0.47) | PTPN11L3MBTL1CA1CA2ENPP3 | |
| SCHEMBL31396553 | 0.83 | PTPN11 (0.54) | PTPN11L3MBTL1CA1CA2ENPP3 | |
| SCHEMBL720190 | 0.83 | PTPN11 (0.49) | PTPN11L3MBTL1ENPP3ENPP1MEN1 | |
| SCHEMBL31396517 | 0.83 | PTPN11 (0.49) | PTPN11L3MBTL1CA1CA2ENPP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685490-B | Pyrrolopyridine compound and application thereof | 南京再明医药有限公司 | 2025-03-28 | — | — | CN | disclosed |