SCHEMBL31554469

SCHEMBL31554469

COc1cc2ncc(F)c(Oc3c(F)cc(N)cc3F)c2cc1OC

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KIT P10721 2/20 0.48
PDGFRB P09619 1/20 0.44
PDGFRA P16234 1/20 0.44
PDPK1 O15530 3/20 0.42
SRC P12931 1/20 0.42
KDR P35968 3/20 0.41
TRPA1 O75762 1/20 0.41
CSF1R P07333 5/20 0.39
NUDT1 P36639 1/20 0.39
EGFR P00533 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31554494 0.85 KIT (0.45) KITPDGFRBPDGFRAPDPK1SRC
SCHEMBL31554419 0.85 KIT (0.54) KITPDGFRBPDGFRAPDPK1SRC
SCHEMBL31554530 0.80 PDGFRB (0.41) KITPDGFRBPDGFRAPDPK1TRPA1
SCHEMBL14967538 0.80 PDGFRB (0.57) KITPDGFRBPDGFRAKDREGFR
SCHEMBL31554537 0.78 AXL (0.51) KITPDPK1SRCKDRTRPA1
SCHEMBL31554548 0.76 AXL (0.45) KITPDGFRBPDGFRAPDPK1KDR
SCHEMBL24009146 0.74 PDPK1 (0.47) KITPDGFRBPDGFRAPDPK1KDR
SCHEMBL25278689 0.73 AXL (0.50) PDGFRBPDGFRAEGFR
SCHEMBL25258996 0.73 PDGFRB (0.49) KITPDGFRBPDGFRAKDREGFR
SCHEMBL5054175 0.72 SRC (0.60) KITSRCEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096463-A1 PLK4 MODULATORS VIBLIOME THERAPEUTICS, LLC (US) 2025-05-08 WO disclosed