Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19645707 | 0.86 | PDGFRB (0.53) | PDPK1PDGFRBPDGFRAIRAK1IRAK4 | |
| SCHEMBL2063193 | 0.85 | PDGFRB (0.52) | PDPK1PDGFRBPDGFRAIRAK1IRAK4 | |
| SCHEMBL31554474 | 0.85 | PDGFRB (0.52) | PDPK1PDGFRBPDGFRAIRAK1IRAK4 | |
| SCHEMBL256577 | 0.84 | PDPK1 (0.47) | PDPK1KITKDM4ESRCFLT1 | |
| SCHEMBL12335689 | 0.83 | PDGFRB (0.50) | PDPK1PDGFRBPDGFRAIRAK1IRAK4 | |
| SCHEMBL5929704 | 0.83 | CSF1R (0.57) | PDPK1EGFR | |
| SCHEMBL5929634 | 0.83 | CSF1R (0.57) | PDPK1EGFR | |
| SCHEMBL1893875 | 0.82 | SRC (0.61) | PDGFRBPDGFRAEGFRKDRSRC | |
| SCHEMBL5452461 | 0.82 | EGFR (0.49) | PDPK1PDGFRBPDGFRAIRAK1IRAK4 | |
| SCHEMBL15263519 | 0.82 | SRC (0.61) | PDGFRBPDGFRAEGFRKDRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096463-A1 | PLK4 MODULATORS | VIBLIOME THERAPEUTICS, LLC (US) | 2025-05-08 | — | — | WO | disclosed |