Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19645707 | 0.83 | PDGFRB (0.53) | EGFRKDRSRCPDGFRBPDGFRA | |
| SCHEMBL31554474 | 0.82 | PDGFRB (0.52) | EGFRKDRSRCPDGFRBPDGFRA | |
| SCHEMBL2063193 | 0.82 | PDGFRB (0.52) | EGFRKDRSRCPDGFRBPDGFRA | |
| SCHEMBL31554584 | 0.82 | PDPK1 (0.54) | EGFRKDRSRCPDGFRBPDGFRA | |
| SCHEMBL15263519 | 0.82 | SRC (0.61) | EGFRKDRSRCPDGFRBPDGFRA | |
| SCHEMBL1893875 | 0.82 | SRC (0.61) | EGFRKDRSRCPDGFRBPDGFRA | |
| SCHEMBL12335689 | 0.81 | PDGFRB (0.50) | EGFRKDRSRCPDGFRBPDGFRA | |
| SCHEMBL5929650 | 0.80 | EGFR (0.53) | EGFRPDGFRBPDGFRAPDPK1KDM1A | |
| SCHEMBL2063533 | 0.79 | IRAK1 (0.53) | EGFRKDRSRCPDGFRBPDGFRA | |
| SCHEMBL168494 | 0.78 | PIN1 (0.49) | PDGFRBPDGFRAPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208164-A1 | Methods of synthesizing radiolabeled 3-cyano[14C]quinolines | WYETH (US) | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208164-A1 | Methods of synthesizing radiolabeled 3-cyano[14C]quinolines | QPCT, RECQL, CBR3 | EGFR 2355/4885KDR 3819/4885SRC 3839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.